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In Silico Biology

In Silico Biology

Journal of Biological Systems Modeling and Multi-Scale Simulation
Published in Association with IOS Press

eISSN: 14343207 | ISSN: 13866338


The term "in silico" is a pendant to "in vivo" (in the living system) and "in vitro" (in the test tube) biological experiments, and implies the gain of insights by computer-based simulations and model analyses.

In Silico Biology (ISB) was founded in 1998 as a purely online journal. IOS Press became the publisher of the printed journal shortly after. Today, ISB is dedicated exclusively to biological systems modeling and multi-scale simulations and is published solely by IOS Press. The previous online publisher, Bioinformation Systems, maintains a website containing studies published between 1998 and 2010 for archival purposes.

We strongly support open communications and encourage researchers to share results and preliminary data with the community. Therefore, results and preliminary data made public through conference presentations, conference proceeding or posting of unrefereed manuscripts on preprint servers will not prohibit publication in ISB. However, authors are required to modify a preprint to include the journal reference (including DOI), and a link to the published article on the ISB website upon publication.

Submit your manuscript today at https://www2.cloud.editorialmanager.com/isb/default.aspx.

In Silico Biology is a scientific research journal for the advancement of computational models and simulations applied to complex biological phenomena. We publish peer-reviewed leading-edge biological, biomedical and biotechnological research in which computer-based (i.e., "in silico") modeling and analysis tools are developed and utilized to predict and elucidate dynamics of biological systems, their design and control, and their evolution. Experimental support may also be provided to support the computational analyses.

In Silico Biology aims to advance the knowledge of the principles of organization of living systems. We strive to provide computational frameworks for understanding how observable biological properties arise from complex systems. In particular, we seek for integrative formalisms to decipher cross-talks underlying systems level properties, ultimate aim of multi-scale models.

Studies published in In Silico Biology generally use theoretical models and computational analysis to gain quantitative insights into regulatory processes and networks, cell physiology and morphology, tissue dynamics and organ systems. Areas of interest include signal transduction and information processing, gene expression and gene regulatory networks, metabolism, proliferation, differentiation and morphogenesis, among others. Multi-scale modeling to connect molecular and cellular systems to the level of organisms and populations, interface between -omics integration and modeling, and development of algorithms for modeling purposes are of particular interest.

In Silico Biology also publishes foundational research in which novel algorithms are developed to facilitate modeling and simulations. Such research must demonstrate application to a concrete biological problem.

The term "in silico" is a pendant to "in vivo" (in the living system) and "in vitro" (in the test tube) biological experiments, and implies the gain of insights by computer-based simulations and model analyses.

In Silico Biology frequently publishes special issues on seminal topics and trends. Special issues are handled by Special Issue Editors appointed by the Editor-in-Chief. Proposals for special issues should be sent to the Editor-in-Chief.

Editor-in-Chief
Brian Ingalls University of Waterloo, Canada
Former Editors-in-Chief
Matteo Barberis University of Surrey, United Kingdom
Mads Kaern Canada
Jack Leunissen † The Netherlands
Edgar Wingender Germany
Advisory Board Members
John Aitchison Institute for Systems Biology, USA
Matteo Barberis University of Surrey, United Kingdom
Dennis Bray University of Cambridge, United Kingdom
Roland Eils University of Heidelberg, Germany
Albert Goldbeter Université Libre de Bruxelles, Belgium
Hiroaki Kitano The Systems Biology Institute, Japan
Michael Mackey McGill University, Canada
John Tyson Virginia Tech, USA
Hans Westerhoff University of Manchester, United Kingdom
Editorial Board Members
Ilya Akberdin Institute of Cytology and Genetics, Russia
Gábor Balázsi University of Texas, USA
Daniel Charlebois Stony Brook University, USA
Sangdun Choi Ajou University, Korea
Daniel Coombs University of British Columbia, Canada
Diego Di Bernardo Telethon Institute for Genetics and Medicine, Italy
Eldon Emberly Simon Fraser University, Canada
Johannes Jaeger Centre for Genomic Regulation, Spain
Yves Lussier University of Chicago, USA
Ion Mandoiu University of Connecticut, USA
William Mather Virginia Tech, USA
Nicolas Mermod University of Lausanne, Switzerland
David Miquez Gómez Universidad Autónoma de Madrid, Spain
Theodore Perkins Ottawa Hospital Research Institute, Canada
Peter Swain University of Edinburgh, Scotland, UK
André Ribeiro Tampere University of Technology, Finland
Moisés Santillán Centre for Research and Advanced Studies, Mexico
Kumar Selvarajoo Keio University, Japan
Thangavelu Srinivasan Indian Institute of Science, India
Jose Vilar University of the Basque Country, Spain
Xiao Wang Arizona State University, USA
  • EBSCO
  • PubMed Central (PMC)
  • PubMed: MEDLINE
  • Scopus