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The Therapeutic Advances series: Cross COVID-19 Collection


This article collection is compiled of research from the Therapeutic Advance Series, covering content relating to COVID-19.


SARS-CoV-2 RNA in the Cerebrospinal Fluid of a Patient with Long COVID

Lung microbiota dysbiosis and the implications of SARS-CoV-2 infection in pregnancy

The emerging SARS-CoV-2 variants of concern

Preventing SARS-CoV-2 infection by blocking a tissue serine protease

Prognostic factors in cancer patients infected with SARS-CoV-2: a Latin American country results

Oral disease-modifying antirheumatic drugs and immunosuppressants with antiviral potential, including SARS-CoV-2 infection: a review

Treatment of severe acute ulcerative colitis in SARS-CoV-2 infected patients: report of three cases and discussion of treatment options

Methods to disinfect and decontaminate SARS-CoV-2: a systematic review of in vitro studies

The complex relationship between viruses and inflammatory bowel disease – review and practical advices for the daily clinical decision-making during the SARS-CoV-2 pandemic

Involvement of digestive system in COVID-19: manifestations, pathology, management and challenges

Mechanisms and management of prothrombotic state in COVID-19 disease

Ocular manifestations of COVID-19

Management of a Parkinson’s disease patient with severe COVID-19 pneumonia

Safety of fecal microbiota transplantation for Clostridioides difficile infection focusing on pathobionts and SARS-CoV-2

Convalescent Blood Products in COVID-19: A Narrative Review

Systematic review and meta-analysis of clinical outcomes of COVID-19 patients undergoing gastrointestinal endoscopy

COVID-19 and conjunctivitis: a meta-analysis

SARS-CoV-2: the endocrinological protective clinical model derived from patients with prostate cancer

Missed opportunities to identify cryptococcosis in COVID-19 patients: a case report and literature review

The gut microbiome: an under-recognised contributor to the COVID-19 pandemic?

Androgen-deprivation therapy and SARS-Cov-2 infection: the potential double-face role of testosterone

Convalescent plasma appears efficacious and safe in COVID-19

Impact of COVID-19 outbreak in an Italian cohort of patients with systemic sclerosis

Optimizing diabetes mellitus care to improve COVID-19 outcomes in resource-limited settings in Africa

The impact of COVID-19 on tuberculosis: challenges and opportunities

Treatment with eltrombopag of severe immune thrombocytopenia and hemolytic anemia associated with COVID-19 pneumonia: a case report

Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection

Analysis of the effects of the first and second/third waves of the COVID-19 pandemic on an Interdisciplinary Endoscopy Unit in a German ‘hotspot’ area: a single-center experience

Differences in RAAS/vitamin D linked to genetics and socioeconomic factors could explain the higher mortality rate in African Americans with COVID-19

Chloroquine and hydroxychloroquine as a repurposed agent against COVID-19: a narrative review

Technical and clinical outcomes of endoscopic retrograde cholangiopancreatography (ERCP) procedures performed in patients with COVID-19

COVID-19 vaccine acceptance among high-risk populations in Uganda

Bilio-pancreatic endoscopy during COVID-19 pandemic

Retinal vascular findings in patients with COVID-19

Symptom cluster analysis of long COVID-19 in patients discharged from the Temporary COVID-19 Hospital in Mexico City

Assessment of corneal endothelial cell morphology and anterior segment parameters in COVID-19

How to get away with COVID-19: endoscopy during post-peak pandemic. A perspective review

Covid-19 and the management of patients with inflammatory bowel disease: a practical decalogue for the post-pandemic phase

Tocilizumab and liver injury in patients with COVID-19

Bacterial co-infections and antibiotic prescribing practice in adults with COVID-19: experience from a single hospital cluster

Influence of colchicine prescription in COVID-19-related hospital admissions: a survival analysis

A review on recipients of hematopoietic stem cell transplantation patients with COVID-19 infection

Clinical characteristics of COVID-19 patients with complications: implications for management

Management of clozapine treatment during the COVID-19 pandemic

Why such excess of mortality for COVID-19 in Spain?

The effect of COVID-19 on absolute neutrophil counts in patients taking clozapine

Pharmacotherapeutic approach toward urological medications and vaccination during COVID-19: a narrative review

Immunogenicity and safety of inactivated and mRNA COVID-19 vaccines in patients with systemic lupus erythematosus

Cardiovascular risk factors and clinical outcomes of patients hospitalized with COVID-19 pneumonia in Somalia

Dipeptidyl peptidase-4 inhibitor use and mortality in COVID-19 patients with diabetes mellitus: an updated systematic review and meta-analysis

Probiotics use is associated with improved clinical outcomes among hospitalized patients with COVID-19

The importance of physical activity in management of type 2 diabetes and COVID-19

Current smoking, former smoking, and adverse outcome among hospitalized COVID-19 patients: a systematic review and meta-analysis

Possible unrecognised liver injury is associated with mortality in critically ill COVID-19 patients

Mortality related to COVID-19 in patients with rheumatic and musculoskeletal diseases, first wave of the outbreak: a single-center study

COVID-19 and post-infectious myalgic encephalomyelitis/chronic fatigue syndrome: a narrative review

COVID-19 vaccine hesitancy among staff and students in a Nigerian tertiary educational institution

Emerging and experimental treatments for COVID-19 and drug interactions with psychotropic agents

Effect of COVID-19 pandemic on the workflow of endoscopy units: an international survey

COVID-19: a review of current knowledge regarding exposure, quarantine, isolation and other preventive measures

The impact of a dedicated contact centre on the clinical outcome of patients with inflammatory bowel disease during the COVID-19 outbreak

Early fibroproliferative signs on high-resolution CT are associated with mortality in COVID-19 pneumonia patients with ARDS: a retrospective study

Remdesivir use and outcomes during the FDA COVID-19 emergency use authorization period

Impact of COVID-19-associated anxiety on the adherence to intravitreal injection in patients with macular diseases a year after the initial outbreak

Impact of preemptive hospitalization on health outcomes at the temporary COVID-19 hospital in Mexico City: a prospective observational study

Elevated glycohemoglobin is linked to critical illness in COVID-19: a retrospective analysis

The neurological symptoms of COVID-19: a systematic overview of systematic reviews, comparison with other neurological conditions and implications for healthcare services

High expression of neutrophil and monocyte CD64 with simultaneous lack of upregulation of adhesion receptors CD11b, CD162, CD15, CD65 on neutrophils in severe COVID-19

Hospital admissions in inflammatory rheumatic diseases during the peak of COVID-19 pandemic: incidence and role of disease-modifying agents

Vitamin D in the time of the coronavirus (COVID-19) pandemic – a clinical review from a public health and public mental health perspective

How did the first year of the COVID-19 pandemic affect urology practice in Arab countries? A cross-sectional study by the Arab Association of Urology research group

Keeping alive enterprises while embracing unprecedented COVID-19 restrictions

Benefits of COVID-19 viral screening of formerly incarcerated individuals during community reentry

COVID-19 associated mucormycosis: the urgent need to reconsider the indiscriminate use of immunosuppressive drugs

Overt and non-overt disseminated intravascular coagulation and the potential role of heparin in the COVID-19 pandemic outbreak

Knowledge and awareness of COVID-19 epidemic preparedness and response among health care workers in Makkah city

Understanding the clinical utility of favipiravir (T-705) in coronavirus disease of 2019: a review

Neurological manifestations of long-COVID syndrome: a narrative review

Management of anti-VEGF intravitreal treatment at University Hospital Federico II of Naples during COVID-19 pandemic lockdown

Personal protective equipment use by healthcare workers in intensive care unit during the early phase of COVID-19 pandemic in Italy: a secondary analysis of the PPE-SAFE survey

Structural reorganization of the ophthalmological practice in a COVID-19 hub hospital: experience from European epicenter of the pandemic

Does the direct renin inhibitor have a role to play in attenuating severity of the outbreak coronavirus disease 2019 (COVID-19)?

Insights into the management of anorectal disease in the coronavirus 2019 disease era

Fecal microbiota transplantation for recurrent Clostridioides difficile, safety, and pitfalls

A glimpse into the future of systemic lupus erythematosus

Tying the past to the present: time tested knowledge with state-of-the-art technology in the fight against emerging and drug resistant microbes

Telemedicine in clinical gastroenterology practice: what do patients prefer?

The elderly IBD patient in the modern era: changing paradigms in risk stratification and therapeutic management

The role of bronchoscopy in the diagnosis and management of pediatric pulmonary tuberculosis

Clostridioides difficile infection: curbing a difficult menace

A narrative review of current evidence supporting the implementation of electronic patient-reported outcome measures in the management of chronic diseases

The role of gut mycobiome in health and diseases

The role of faecal microbiota transplantation: looking beyond Clostridioides difficile infection

Hydroxychloroquine in systemic lupus erythematosus: overview of current knowledge

Neuro-axonal injury in COVID-19: the role of systemic inflammation and SARS-CoV-2 specific immune response

Comprehensive literature review on COVID-19 vaccines and role of SARS-CoV-2 variants in the pandemic

Oropharyngeal swab for SARS-CoV-2 test causing atypical internal carotid artery dissection and stroke in a patient after mild COVID-19

Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection

Observational cohort study of neurological involvement among patients with SARS-CoV-2 infection

COVID-19 and cerebrovascular diseases: a comprehensive overview

Neurological manifestations and implications of COVID-19 pandemic

Oxygen therapy via high flow nasal cannula in severe respiratory failure caused by Sars-Cov-2 infection: a real-life observational study

The use of nebulized pharmacotherapies during the COVID-19 pandemic

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

Humoral immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis treated with high-efficacy disease-modifying therapies

Can we develop oncolytic SARS-CoV-2 to specifically target cancer cells?

Symptomatic COVID-19 in advanced-cancer patients treated with immune-checkpoint inhibitors: prospective analysis from a multicentre observational trial by FICOG

Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective

Doxycycline treatment of high-risk COVID-19-positive patients with comorbid pulmonary disease

Extensive cerebellar involvement and cognitive impairment in COVID-19-associated acute necrotizing encephalopathy

Three-month outcomes of recovered COVID-19 patients: prospective observational study

COVID-19 in cancer patients on systemic anti-cancer therapies: outcomes from the CAPITOL (COVID-19 Cancer PatIenT Outcomes in North London) cohort study

Identifying higher risk subgroups of health care workers for priority vaccination against COVID-19

Therapeutic interventions for COVID-19: a living overview of reviews

Drug safety of frequently used drugs and substances for self-medication in COVID-19

IgG antibody titers to SARS-CoV-2 reveal a distinct efficacy of multiple sclerosis-modifying therapies to curtail lymphocyte compartments

Potential specific therapies in COVID-19

Renin–angiotensin–aldosterone system blockers and region-specific variations in COVID-19 outcomes: findings from a systematic review and meta-analysis

Early predictors for mechanical ventilation in COVID-19 patients

Targeting the gut–lung microbiota axis by means of a high-fibre diet and probiotics may have anti-inflammatory effects in COVID-19 infection

Systematic review of immunosuppressant guidelines in the COVID-19 pandemic

Transdermal approaches to vaccinations in the COVID-19 pandemic era

Dysfunction of adaptive immunity is related to severity of COVID-19: a retrospective study

High flow nasal cannula oxygenation in COVID-19 related acute respiratory distress syndrome: a safe way to avoid endotracheal intubation?

Does pre-existent physical inactivity have a role in the severity of COVID-19?

TNFα inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis

Potential neurological symptoms of COVID-19

Effectiveness of corticosteroids on chest high-resolution computed tomography features of COVID-19 pneumonia

Routine use of immunosuppressants is associated with mortality in hospitalised patients with COVID-19

Outcome of oncological patients admitted with COVID-19: experience of a hospital center in northern Italy

The predictive role of lymphocyte subsets and laboratory measurements in COVID-19 disease: a retrospective study

Pregnancy and breastfeeding during COVID-19 pandemic

ICU outcomes in Covid-19 patients with obesity

Definition and retrospective application of a clinical scoring system for COVID-19 triage at presentation

Effectiveness of the use of a high-flow nasal cannula to treat COVID-19 patients and risk factors for failure: a meta-analysis

Persistent decline of hospitalizations for acute stroke and acute coronary syndrome during the second wave of the COVID-19 pandemic in Greece: collateral damage unaffected

Worrying situation regarding the use of dexamethasone for COVID-19

High-flow nasal cannula versus noninvasive ventilation in patients with COVID-19: a systematic review and meta-analysis

Impact of bronchiectasis on susceptibility to and severity of COVID-19: a nationwide cohort study

Clinical characteristics and risk factors for severity of COVID-19 outside Wuhan: a double-center retrospective cohort study of 213 cases in Hunan, China

C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis

Respiratory viral infections in the elderly

Mortality, seasonal variation, and susceptibility to acute exacerbation of COPD in the pandemic year: a nationwide population study

Utilizing telehealth to create a clinical model of care for patients with Batten disease and other rare diseases

Post-infectious neurological disorders

Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper)

MOG antibody–associated encephalomyelitis mimicking bacterial meningomyelitis following ChAdOx1 nCoV-19 vaccination: a case report

Outcomes of the 2019 novel coronavirus in patients with or without a history of cancer: a multi-centre North London experience

The safety, tolerability and mortality reduction efficacy of remdesivir; based on randomized clinical trials, observational and case studies reported safety outcomes: an updated systematic review and meta-analysis

COVID-19 vaccine hesitancy: Pakistan struggles to vaccinate its way out of the pandemic

Translating evidence into practice during the COVID-19 pandemic: pitfalls and mileages

Hydroxychloroquine and chloroquine for COVID-19: psychiatric aspects of patient safety considerations

Patients with locally advanced and metastatic cutaneous squamous cell carcinoma treated with immunotherapy in the era of COVID-19: stop or go? Data from five Italian referral cancer centers

Low rate of COVID-19 vaccination in Africa: a cause for concern

COVID-19: should oral vaccination strategies be given more consideration?

Adverse events following COVID-19 vaccination: first 90 days of experience from a tertiary care teaching hospital in South India

The impact of the COVID-19 pandemic on hospitalizations and plasmapheresis therapy in multiple sclerosis and neuromyelitis optica spectrum disorder: a nationwide analysis from Germany