Toxicology and Industrial Health

Toxicology and Industrial Health

2014 Impact Factor: 1.859
2014 Ranking: 71/162 in Public, Environmental & Occupational Health (SCI) | 61/87 in Toxicology
Source: 2014 Journal Citation Reports ® (Thomson Reuters, 2015)

Editors Emeritus
Ronald W Hart Little Rock, Arkansas, USA
Myron Mehlman Princeton, USA
Editor in Chief

eISSN: 14770393| ISSN: 07482337|Current volume: 31|Current issue: 2 Frequency: Monthly

Toxicology & Industrial Health invites manuscripts reporting results of basic and applied toxicological research with direct application to industrial/public health. Such research includes the fields of genetic and cellular toxicology and risk assessment associated with hazardous wastes and groundwater.

The journal publishes original research, reviews on subjects of contemporary importance to toxicologists, pharmacologists, and biochemists, technical reports, and meeting proceedings. The journal considers the results of rigorous, well-designed studies that demonstrate “no effect” or that fail to replicate previous work (“negative data”) as important to the advancement of science.

This journal is a member of the Committee on Publication Ethics (COPE)

Toxicology & Industrial Health is a journal dedicated to reporting results of basic and applied toxicological research with direct application to industrial/public/occupational health. Such research includes the fields of genetic and cellular toxicology and risk assessment associated with hazardous wastes and groundwater.

The journal publishes international peer reviewed original research and reviews on subjects of contemporary importance to toxicologists, pharmacologists, and biochemists, technical reports, and meeting proceedings. The journal considers the results of rigorous, well-designed studies that demonstrate “no effect” or that fail to replicate previous work (“negative data”) as important to the advancement of science.

This journal is a member of the Committee on Publication Ethics (COPE)

Associate Editors
Girish B.Chandrashekaraiah M.V.Sc, DABT Karnataka Veterinary and Animal Sciences University, India
Thomas F. X. Collins, Ph.D Consultant in Toxicology, USA
Guor-Cheng Fang, Ph.D HungKuang University, Taiwan
Xinsheng Gu, Ph.D Hubei University of Medicine, China
Alan M. Hoberman, Ph.D, DABT Charles River Laboratories, USA
Ivo Iavicoli, MD, Ph.D Institute of Public Health, Italy
Vijayalakshmi Ravindranath, Ph.D Centre for Neuroscience, Indian Institute of Science, Bengaluru, India
Wendy Wang, MD, CPH, DABT Dow Chemical Company, USA
Editorial Advisors
Arthur Frank, MD, Ph.D Drexel University, USA
Richard A. Lemen, Ph.D., MSPH United States Public Health Service (retired), USA
Howard L. Maibach, MD University of California Medical Center, USA
Albert E. Munson, Ph.D National Institute for Occupational Safety and Health, USA
Editorial Board
Mohammed Abou-Donia Ph.D., DABT, ATS Duke University, USA
Sabry M. Attia, Ph.D King Saud University, Saudi Arabia
Shelly Bhattacharya, Ph.D Visva-Bharati University, India
Michael R. Bleavins, Ph.D., DABT White Crow Innovation, LLC, USA
Stephen C. Bondy, Ph.D University of California, USA
William J. Brock, Ph.D., DABT, Fellow ATS Brock Scientific Consulting, USA
Jose Alberto Castro, MD Citefa/Conicet, Argentina
Peter Fu, Ph.D National Center for Toxicological Research, AR, USA
Philip Harvey, Ph.D Consultant Toxicologist, UK
Ryan C Lewis, PhD, CIH Exponent, Inc., USA
Ge Lin, Ph.D The Chinese University of Hong Kong, China
Michael Maier Ph.D., CIH, DABT University of Cincinnati, USA
Craig Marcus, Ph.D Oregon State University, USA
Natalia Pawlas, MD, Ph.D Institute of Occupational Medicine and Environmental Health, Poland
Yong Qian Ph.D National Institute for Occupational Safety and Health (NIOSH), USA
Rudy J. Richardson, ScD, DABT University of Michigan, USA
Robert Roy, Ph.D, DABT 3M Company, MN, USA
Haiyan Xu, Ph.D, ERT Toxicology Baxter Healthcare (Suzhou) Co. Ltd., China
Serkan Yilmaz, Ph.D Ankara University, Turkey
Leshuai Zhang, Ph.D Soochow University, China
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    1. Peer review policy
    2. Authorship
    3. Article types
      3.1 Summary of manuscript structure/style
    4. How to submit your manuscript
    5. Journal contributor’s publishing agreement
      5.1 SAGE Choice
    6. Declaration of conflicting interests policy
    7. Other conventions
      7.1 Informed consent
      7.2 Ethics
    8. Acknowledgments
      8.1 Funding acknowledgement
    9. Permissions
    10. Manuscript style
      10.1 File types
      10.2 Journal style
      10.3 Reference style
      10.4 Manuscript preparation
      10.4.1 Keywords and abstracts: Helping readers find your article online
      10.4.2 Corresponding author contact details
      10.4.3 Guidelines for submitting artwork, figures and other graphics
      10.4.4 Guidelines for submitting supplemental files
      10.4.5 English language editing services
    11. After acceptance
      11.1 Proofs
      11.2 E-Prints and complimentary copies
      11.3 SAGE production
      11.4 OnlineFirst publication

    Toxicology & Industrial Health welcomes manuscripts dealing with basic and applied research in the fields of toxicology, genetic and cellular toxicology and risk assessment associated with hazardous wastes and groundwater. The journal will accept and rapidly publish brief communications reporting on important research.


    1. Peer review policy

    Toxicology and Industrial Health adheres to a rigorous double-blind reviewing policy in which the identity of both the reviewer and author are always concealed from both parties, so there is no possibility of bias in any editorial decision.

    Referees will be encouraged to provide substantive, constructive reviews that provide suggestions for improving the work and distinguish between mandatory and non-mandatory recommendations.

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    2. Authorship

    Papers should only be submitted for consideration once all contributing authors have agreed the content of the paper. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. The contribution of each author to the research/review should be defined and each must meet all the following criteria as defined by ICMJE:

    (i) Made a substantial contribution to the concept and design; or the acquisition, analysis or interpretation of data for the work

    (ii) Drafted the article or revised it critically for important intellectual content.

    (iii) Approved the version to be published.

    (iv) Agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work were appropriately investigated and resolved.

    When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship. All contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section.

    ICMJE recommendations:

    COPE Report 2003:

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    3. Article types

    Manuscripts are considered for publication with the understanding that they have not been published previously and are not under consideration by another publication.

    The journal publishes several types of articles including papers describing original research, reviews on subjects of contemporary importance to toxicologists and biochemical scientists; reports or proceedings, which will be published as supplements to issues of the journal at the expense of the organization that submits the proceedings and brief announcements of scientific meetings or courses of interest to readers.

    This journal will not accept papers on herbal extractions or solvents in water.

    3.1 Summary of manuscript structure:

    All manuscripts should be typed and double-spaced.

    Title Page: In addition to the title, this page should include the full name and affiliation for each author. Also indicate which author should be the corresponding author and provide a full mailing address, phone and fax numbers and e-mail address. Please include a running title limited to 50 characters and provide up to 6 key words applicable to the content of the manuscript.

    Text: Papers are to be organized into Abstract, keywords, Introduction, Methods, Results, Discussion, Acknowledgements, and References sections.

    References and Notes: References are listed alphabetically by surname of the first author at the end of each manuscript. Articles cited within the text are listed as follows: if one author, by surname of the first author and year of publication; up to six authors, by the surnames of authors and year of publication; more than six authors, by surname of the first three authors followed by the phrase 'et al.,' and year of publication. Consecutive citations in the text are placed in chronological order and separated by semicolons.

    Do not use abbreviations for the titles of periodicals. References should include authors' last names and initials, article title, journal, volume, page range, and year. Include the city and publisher's name for books. For further information, consult the American Medical Association Manual of Style.

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    4. How to submit your manuscript

    Before submitting your manuscript, please ensure you carefully read and adhere to all the guidelines and instructions to authors provided below. Manuscripts not conforming to these guidelines may be returned.

    Toxicology and Industrial Health has a fully web-based system for the submission and review of manuscripts. All submissions should be made online at the Toxicology and Industrial Health SAGETRACK website:

    Note: Online submission and review of manuscripts is now mandatory for all types of papers.

    New User Account
    Please log onto the website. If you are a new user, you will first need to create an account. Follow the instructions and please ensure to enter a current and correct email address. Creating your account is a three-step process that takes a matter of minutes. When you have finished, your User ID and password is sent immediately via email. Please edit your user ID and password to something more memorable by selecting 'edit account' at the top of the screen. If you have already created an account but have forgotten your details type your email address in the 'Password Help' to receive an emailed reminder. Full instructions for uploading the manuscript are provided on the website.

    New Submission
    Submissions should be made by logging in and selecting the Author Centre and the 'Click here to Submit a New Manuscript' option. Follow the instructions on each page, clicking the 'Next' button on each screen to save your work and advance to the next screen. If at any stage you have any questions or require the user guide, please use the 'Get Help Now' button at the top right of every screen. Further help is available through ScholarOne's® Manuscript CentralTM customer support at +1 434 817 2040 x 167 or email the editor with your manuscript as an attachment(s) and write a note to explain why you need to submit via this route. 

    To upload your files, click on the 'Browse' button and locate the file on your computer. Select the designation of each file (i.e. main document, submission form, figure) in the drop down menu next to the browse button. When you have selected all the files you wish to upload, click the 'Upload Files' button.

    Review your submission (in both PDF and HTML formats) and then click the Submit button
    You may suspend a submission at any point before clicking the Submit button and save it to submit later. After submission, you will receive a confirmation e-mail. You can also log back into your author centre at any time to check the status of your manuscript.

    Please ensure that you submit editable/source files only (Microsoft Word or RTF) and that your document does not include page numbers; the SAGETRACK system will generate them for you, and then automatically convert your manuscript to PDF for peer review. All correspondence, including notification of the Editor's decision and requests for revisions, will be by email.

    If you would like to discuss your paper prior to submission contact the Editor:

    If you seek advice on the submission process please contact the Publishing Editor:

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    5. Journal contributor’s publishing agreement   
    Before publication, SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. SAGE’s Journal Contributor’s Publishing Agreement is a exclusive licence agreement which means that the author retains copyright in the work but grants SAGE the sole and exclusive right and licence to publish for the full legal term of copyright.  Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than SAGE. In this case copyright in the work will be assigned from the author to the society. For more information please visit our Frequently Asked Questions on the SAGE Journal Author Gateway.

    5.1 SAGE Choice
    If you wish your article to be freely available online immediately upon publication (as some funding bodies now require), you can opt for it to be included in SAGE Choice subject to payment of a publication fee. The manuscript submission and peer reviewing procedure is unchanged. On acceptance of your article, you will be asked to let SAGE know directly if you are choosing SAGE Choice. For further information, please visit SAGE Choice.

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    6. Declaration of conflicting interests                  
    Within your Journal Contributor’s Publishing Agreement you will be required to make a certification with respect to a declaration of conflicting interests. It is the policy of Toxicology and Industrial Health to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.

    Please include any declaration at the end of your manuscript after any acknowledgements and prior to the references, under a heading ‘Conflict of Interest Statement’. If no declaration is made, the following will be printed under this heading in your article: ‘None Declared’. Alternatively, you may wish to state that ‘The Author(s) declare(s) that there is no conflict of interest’. 

    When making a declaration, the disclosure information must be specific and include any financial relationship that all authors of the article have with any sponsoring organization and the for-profit interests that the organisation represents, and with any for-profit product discussed or implied in the text of the article.

    Any commercial or financial involvements that might represent an appearance of a conflict of interest need to be additionally disclosed in the covering letter accompanying your article to assist the Editor in evaluating whether sufficient disclosure has been made within the Conflict of Interest statement provided in the article.

    For more information please visit the SAGE Journal Author Gateway.

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    7. Other conventions

    7.1 Informed consent
    Authors are required to ensure that the following guidelines are followed, as recommended by the International Committee of Medical Journal Editors ("Uniform Requirements for Manuscripts Submitted to Biomedical Journals":
    Patients have a right to privacy that should not be infringed without informed consent. Identifying information, including patients' names, initials, or hospital numbers, should not be published in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian) gives written informed consent for publication. Informed consent for this purpose requires that a patient who is identifiable be shown the manuscript to be published.
    Complete anonymity is difficult to achieve, however, and informed consent should be obtained if there is any doubt. For example, masking the eye region in photographs of patients is inadequate protection of anonymity. If identifying characteristics are altered to protect anonymity, such as in genetic pedigrees, authors should provide assurance that alterations do not distort scientific meaning and editors should so note.

    When informed consent has been obtained it should be indicated in the submitted article.

    Authors should identify individuals who provide writing/administrative assistance, indicate the extent of assistanceand disclose the funding source for this assistance.
    Identifying details should be omitted if they are not essential.

    7.2 Ethics
    When reporting experiments on human subjects, indicate whether the procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional or regional) or with the Declaration of Helsinki 1975, revised Hong Kong 1989. Do not use patients' names, initials or hospital numbers, especially in illustrative material. When reporting experiments on animals, indicate which guideline/law on the care and use of laboratory animals was followed.

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    8. Acknowledgements                                                         

    Any acknowledgements should appear first at the end of your article prior to your Declaration of Conflicting Interests (if applicable), any notes and your References.

    All contributors who do not meet the criteria for authorship should be listed in an `Acknowledgements’ section. Examples of those who might be acknowledged include a person who provided purely technical help, writing assistance, or a department chair who provided only general support. Authors should disclose whether they had any writing assistance and identify the entity that paid for this assistance.

    8.1 Funding Acknowledgement
    To comply with the guidance for Research Funders, Authors and Publishers issued by the Research Information Network (RIN), Toxicology and Industrial Health additionally requires all Authors to acknowledge their funding in a consistent fashion under a separate heading.  All research articles should have a funding acknowledgement in the form of a sentence as follows, with the funding agency written out in full, followed by the grant number in square brackets:

    This work was supported by the Medical Research Council [grant number xxx].

    Multiple grant numbers should be separated by comma and space. Where the research was supported by more than one agency, the different agencies should be separated by semi-colons, with “and” before the final funder. Thus:

    This work was supported by the Wellcome Trust [grant numbers xxxx, yyyy]; the Natural Environment Research Council [grant number zzzz]; and the Economic and Social Research Council [grant number aaaa].

    In some cases, research is not funded by a specific project grant, but rather from the block grant and other resources available to a university, college or other research institution. Where no specific funding has been provided for the research we ask that corresponding authors use the following sentence:

    This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

    Please include this information under a separate heading entitled “Funding” directly after any other Acknowledgements prior to your “Declaration of Conflicting Interests” (if applicable), any Notes and your References.

    For more information on the guidance for Research Funders, Authors and Publishers, please visit:

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    9. Permissions

    Authors are responsible for obtaining permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please visit our Frequently Asked Questions on the SAGE Journal Author Gateway..

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    10. Manuscript style

    10.1 File types
    Only electronic files conforming to the journal's guidelines will be accepted. Preferred formats for the text and tables of your manuscript are Word DOC, and tiff or jpeg for figures (ideally figures will use journal colours). Please also refer to additional guideline on submitting artwork [and supplemental files] below.

    10.2 Journal Style
    Toxicology and Industrial Health conforms to the SAGE house style.  Click here to review guidelines on SAGE UK House Style.

    10.3 Reference Style
    Toxicology and Industrial Health adheres to the SAGE Harvard reference style. Click here to review the guidelines on SAGE Harvard to ensure your manuscript conforms to this reference style.

    If you use EndNote to manage references, download the SAGE Harvard output style by following this link and save to the appropriate folder (normally for Windows C:\Program Files\EndNote\Styles and for Mac OS X Harddrive:Applications:EndNote:Styles). Once you’ve done this, open EndNote and choose “Select Another Style...” from the dropdown menu in the menu bar; locate and choose this new style from the following screen.

    References should include authors' last names and initials, article title, journal, volume, page range, and year. Include the city and publisher's name for books. For further information, consult the American Medical Association Manual of Style.

    Kono K, Harada A, Watanabe T et al. (2002) A long-term surveillance of workers exposed to cadmium. Kankyo Hoken Report.

    Main AR and Braid PE (1962) Hydrolysis of malathion by aliesterase in vitro and in vivo. Biochemical Journal 52:255-263.

    Talcott RE (1980) Microsomal lipid peroxidation: Catalysis, effects, and inhibition by cytosolic protein. In: Coon MJ, Cooney AH and Estabrook RW (eds) Microsomes, Drug Oxidations, and Chemical Carcinogenesis, Vol. 2. New York: Academic Press, pp.753-761.

    10.4. Manuscript Preparation
    The text should be double-spaced throughout and with a minimum of 3cm for left and right hand margins and 5cm at head and foot. Text should be standard 10 or 12 point.

    10.4.1 Keywords and Abstracts: Helping readers find your article online
    The title, keywords and abstract are key to ensuring that readers find your article online through online search engines such as Google. Please refer to the information and guidance on how best to title your article, write your abstract and select your keywords by visiting SAGE’s Journal Author Gateway Guidelines on How to Help Readers Find Your Article Online.

    10.4.2 Corresponding Author Contact details
    Provide full contact details for the corresponding author including email, mailing address and telephone numbers. Academic affiliations are required for all co-authors.

    10.4.3 Guidelines for submitting artwork, figures and other graphics
    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit SAGE’s Manuscript Submission Guidelines.

    Images should be supplied as bitmap based files (i.e. with .tiff or .jpeg extension) with a resolution of at least 300 dpi (dots per inch). Line art should be supplied as vector-based, separate .eps files (not as .tiff files, and not only inserted in the Word or pdf file), with a resolution of 600 dpi. Images should be clear, in focus, free of pixilation and not too light or dark.

    If, together with your accepted article, you submit usable colour figures, these figures will appear in colour online regardless of whether or not these illustrations are reproduced in colour in the printed version. For specifically requested colour reproduction in print, you will receive information regarding the possible costs from SAGE after receipt of your accepted article.

    In text: tables and figures are either inserted as part of a sentence, for example table 1 or in parentheses for example (figure 1). Each table should carry a descriptive heading. Each figure should be submitted electronically.

    Tables. These should be labeled sequentially as Table 1, Table 2, etc. Each table should be typed on a separate page, numbered, titled, and cited in the text. References to table footnotes should be made by means of Arabic numerals.

    Figures. Artwork should be sent electronically in .eps or .tif format, at 300 dots per inch (118 dots per cm) for superior reproduction. Every illustration should have an explanatory legend, and not merely Figure 1, Figure 2 etc.

    10.4.4 Guidelines for submitting supplemental files
    The journal may be able to host approved supplemental materials online, alongside the full-text of articles. Supplemental files will be subjected to peer-review alongside the article. Please contact the Editor ( in the first instance.  For more information please refer to SAGE’s Guidelines for Authors on Supplemental Files.

    10.4.5 English Language Editing services
    Non-English speaking authors who would like to refine their use of language in their manuscripts should have their manuscript reviewed by colleagues with experience of preparing manuscripts in English.

    Alternatively it might be useful to consider using a professional editing service. Visit English Language Editing Services for further information.

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    11. After acceptance           

    11.1 Proofs
    We will email a PDF of the proofs to the corresponding author. Corrections should be limited to typographical amendments. Authors' approval will be assumed if corrections are not returned by the date indicated.

    11.2 E-Prints and Complimentary Copies
    SAGE provides authors with access to a PDF of their final article. For further information please visit Offprints and Reprints.

    11.3 SAGE Production
    At SAGE we place an extremely strong emphasis on the highest production standards possible. We attach high importance to our quality service levels in copy-editing, typesetting, printing, and online publication ( We also seek to uphold excellent author relations throughout the publication process.

    We value your feedback to ensure that we continue to improve our author service levels. On publication all corresponding Authors will receive a brief survey questionnaire on your experience of publishing in Toxicology and Industrial Health with SAGE. 

    11.4 OnlineFirst Publication
    Toxicology and Industrial Health provides the opportunity for your article to be included in OnlineFirst, a feature offered through SAGE’s electronic journal platform, SAGE Journals Online. It allows final revision articles (completed articles in queue for assignment to an upcoming issue) to be hosted online prior to their inclusion in a final print and online journal issue.  This significantly reduces the lead time between submission and publication. For more information please visit our OnlineFirst Fact Sheet

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