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Statistical Methods in Medical Research

Statistical Methods in Medical Research

An International Review Journal

eISSN: 14770334 | ISSN: 09622802 | Current volume: 33 | Current issue: 1 Frequency: Monthly

Statistical Methods in Medical Research is a highly ranked, peer reviewed scholarly journal and is the leading vehicle for articles in all the main areas of medical statistics and therefore an essential reference for all medical statisticians. It is particularly useful for medical researchers dealing with data and provides a key resource for medical and statistical libraries, as well as pharmaceutical companies.

This unique journal is devoted solely to statistics and medicine and aims to keep professionals abreast of the many powerful statistical methods now available to the medical profession. As new methods are constantly adopted by statisticians working both inside and outside the medical environment, this review journal aims to satisfy the increasing demand for accurate and up-to-the-minute information.

Why choose Statistical Methods in Medical Research?

  • Contains both reviews and original papers of the latest statistical developments relevant to medical research
  • Covers all areas of medical statistics
  • Full of well-written papers by leading experts in the field
  • Accessible to a wide audience of medical statisticians and statistically minded medical researchers
  • An indispensable reference for medical statisticians, statistical libraries and pharmaceutical companies.

Books available to review from the US Book Review Editor

Books available to review from the UK Book Review Editor

Click here for the full list of Statistical Methods in Medical Research back issues

This journal is a member of the Committee on Publication Ethics (COPE).

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Statistical Methods in Medical Research is a highly ranked, peer reviewed scholarly journal and is the leading vehicle for review and non-review articles in all the main areas of medical statistics. It is therefore an essential reference for all medical statisticians. It is particularly useful for medical researchers dealing with data and it provides a key resource for medical and statistical libraries, as well as pharmaceutical companies.

This unique journal is devoted solely to statistics and medicine and aims to keep professionals abreast of the many powerful statistical techniques now available to the medical profession. As techniques are constantly adopted by statisticians working both inside and outside the medical environment, this review journal aims to satisfy the increasing demand for accurate and up-to-the-minute information.

Why choose Statistical Methods in Medical Research?

  • Covers all areas of medical statistics
  • Full of statistics and statistical techniques
  • Contains the latest, accurate information
  • An indispensable reference for medical statisticians, statistical libraries and pharmaceutical companies.

Sign up for the latest table of content alerts.

Editor-in-Chief
Marta Garcia-Finana University of Liverpool, UK
Chris Metcalfe Bristol University, UK
Lili Tian The State University of New York (SUNY) at Buffalo, USA
Founding Editors
Graham Dunn University of Manchester, UK
Brian Everitt King's College, London, UK
Theodore Holford Yale University, USA
Associate Editors
Andrew Forbes Monash University, Australia
Roee Gutman Brown University, USA
Yulei He U.S. Centers for Disease Control and Prevention, USA
Torsten Hothorn University of Zurich, Switzerland
David Hughes University of Liverpool, UK
Mizanur Khondoker University of East Anglia, UK
Evangelos Kontopantelis University of Manchester, UK
Dongliang Wang SUNY Upstate Medical University, USA
Editorial Board
Per Andersen University of Copenhagen, Denmark
Sanjib Basu University of Illinois at Chicago, USA
Michael Brammer King's College London, UK
Marc Buyse International Drug Development Institute, Belgium
James Carpenter Ann Arbor, Michigan, USA
K.C. Carriere University of Alberta, USA
Eric Chi North Carolina State University, USA
Itai Dattner University of Haifa, Israel
Daniela De Angelis University of Cambridge, UK
Stephen Duffy Queen Mary University of London, UK
Lisa Hampson Novartis Pharma AG, Switzerland
Brian Healy Harvard Medical School, USA
Theodore Holford Yale University, USA
C Jennison University of Bath, UK
Byron Jones Pfizer Global Research and Development, USA
Mark Kelson Exeter University, UK
Sabine Landau King's College London, UK
Kenneth Lange University of California, Los Angeles, USA
Andrew B Lawson Medical University of South Carolina, USA
Morven Leese King's College London, UK
Ruosha Li The University of Texas Health Science Center at Houston, USA
Xiaomei Liao Harvard University, USA
Ruitao Lin The University of Texas MD Anderson Cancer Center, USA
Aiyi Liu NICHD/NIH, USA
Tanzy Love University of Rochester, USA
Glen Martin University of Manchester, UK
Ben Reiser University of Haifa, Israel
Abdus Sattar Case Western Reserve University, USA
S. Senn Glasgow, UK
Daniel Stahl King's College London, UK
Nigel Stallard University of Warwick, UK
Andrew Titman Lancaster University, UK
Brian D.M. Tom MRC Biostatistics Unit, UK
Mark van der Laan University of California, USA
Bo Wang North Carolina A&T State University, USA
James Wason Newcastle University, UK
Ian White MRC Clinical Trials Unit at UCL, UK
Tu Xu Novo Nordisk, USA
Guan Yu University of Pittsburgh, USA
Bo Zhang Harvard Medical School, USA
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  • Manuscript Submission Guidelines: Statistical Methods in Medical Research

    This Journal is a member of the Committee on Publication Ethics.

    This Journal recommends that authors follow the Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals formulated by the International Committee of Medical Journal Editors (ICMJE).

    Please read the guidelines below then visit the Journal’s submission site http://mc.manuscriptcentral.com/smmr to upload your manuscript. Please note that manuscripts not conforming to these guidelines may be returned.

    Only manuscripts of sufficient quality that meet the aims and scope of Statistical Methods in Medical Research (SMMR) will be reviewed.

    There are no fees payable to submit or publish in this Journal. Open Access options are available - see section 3.3 below.

    As part of the submission process you will be required to warrant that you are submitting your original work, that you have the rights in the work, and that you have obtained and can supply all necessary permissions for the reproduction of any copyright works not owned by you, that you are submitting the work for first publication in the Journal and that it is not being considered for publication elsewhere and has not already been published elsewhere. Please see our guidelines on prior publication and note that Statistical Methods in Medical Research may accept submissions of papers that have been posted on pre-print servers; please alert the Editorial Office when submitting (contact details are at the end of these guidelines) and include the DOI for the preprint in the designated field in the manuscript submission system. Authors should not post an updated version of their paper on the preprint server while it is being peer reviewed for possible publication in the journal. If the article is accepted for publication, the author may re-use their work according to the journal's author archiving policy.

    1. What do we publish?
      1.1 Aims & Scope
      1.2 Article types
      1.3 Writing your paper
    2. Editorial policies
      2.1 Peer review policy
      2.2 Authorship
      2.3 Acknowledgements
      2.4 Funding
      2.5 Declaration of conflicting interests
      2.6 Research ethics and patient consent
      2.7 Clinical trials
      2.8 Reporting guidelines
      2.9 Research Data
    3. Publishing policies
      3.1 Publication ethics
      3.2 Contributor's publishing agreement
      3.3 Open access and author archiving
    4. Preparing your manuscript
      4.1 Formatting
      4.2 Artwork, figures and other graphics
      4.3 Supplemental material
      4.4 Reference style
      4.5 Journal layout
      4.6 English language editing services
    5. Submitting your manuscript
      5.1 ORCID
      5.2 Information required for completing your submission
      5.3 Permissions
    6. On acceptance and publication
      6.1 SAGE Production
      6.2 Online First publication
      6.3 Access to your published article
      6.4 Promoting your article
    7. Further information

    1. What do we publish?

    1.1 Aims & Scope

    Before submitting your manuscript to Statistical Methods in Medical Research, please ensure you have read the Aims & Scope.  

    1.2 Article Types

    The aim of the journal is to publish both review types detailing the way particular statistical methods are (and could be) employed within medical research, and, accounts of innovative methodological developments or applications. The latter, although not review papers per se, should include an introduction that acts as a brief overview of the area to be discussed.

    Both types of paper should include a motivating example or, in some cases, several examples and should be written to be accessible to a broad audience. This implies that material of a very technical nature should be relegated to an appendix.

    The following papers, which have appeared in previous issues, might be taken as good examples of what the journal is aiming for:

    Hudgens MG, Gilbert PB and Self SG. 2004; 13: 89-114 (http://smm.sagepub.com/content/13/2/89.full.pdf+html).
    Zhou H. 2006; 15: 181-194. (http://smm.sagepub.com/content/15/2/181.full.pdf+html)

    Authors should include their name and initials, their affiliations, and their address for correspondence with telephone and fax numbers or email address.

    Papers should be around 8,000 words. Any diagrams or tables should be counted as equivalent to around 200 words or half a page of text. The editor should be informed if this is likely to be a problem.

    An abstract of up to 200 words and a selection of keywords should precede the text. Any acknowledgements or conflicts of interest will be printed at the end of the text.

    All authors need to follow the Statistical Methods in Medical Research reference style, authors that do not will find their paper returned to them. For more information please see 4.4 Reference Style.

    Electronic versions: Microsoft Word is the preferred format, but files can be accepted from any common word processing program. PDF files should only be supplied in addition to source files. PDF files alone are not acceptable.

    1.3 Writing your paper

    The SAGE Author Gateway has some general advice and on how to get published, plus links to further resources. SAGE Author Services also offers authors a variety of ways to improve and enhance their article including English language editing, plagiarism detection, and video abstract and infographic preparation.

    1.3.1 Make your article discoverable

    When writing up your paper, think about how you can make it discoverable. The title, keywords and abstract are key to ensuring readers find your article through search engines such as Google. For information and guidance on how best to title your article, write your abstract and select your keywords, have a look at this page on the Gateway: How to Help Readers Find Your Article Online.

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    2. Editorial policies

    2.1 Peer review policy

    The journal's policy is to obtain at least two independent reviews of each article. It operates a double blind peer reviewing policy in which the reviewer’s name is withheld from the author and, the author’s name from the reviewer. Referees will be encouraged to provide substantive, constructive reviews that provide suggestions for improving the work and distinguish between mandatory and non-mandatory recommendations.

    2.2 Authorship

    Papers should only be submitted for consideration once consent is given by all contributing authors. Those submitting papers should carefully check that all those whose work contributed to the paper are acknowledged as contributing authors.

    The list of authors should include all those who can legitimately claim authorship. This is all those who:

    1. Made a substantial contribution to the concept or design of the work; or acquisition, analysis or interpretation of data,
    2. Drafted the article or revised it critically for important intellectual content,
    3. Approved the version to be published,
    4. Each author should have participated sufficiently in the work to take public responsibility for appropriate portions of the content.

    Authors should meet the conditions of all of the points above. When a large, multicentre group has conducted the work, the group should identify the individuals who accept direct responsibility for the manuscript. These individuals should fully meet the criteria for authorship.

    Acquisition of funding, collection of data, or general supervision of the research group alone does not constitute authorship, although all contributors who do not meet the criteria for authorship should be listed in the Acknowledgments section. Please refer to the International Committee of Medical Journal Editors (ICMJE) authorship guidelines for more information on authorship.

    Please note that AI chatbots, for example ChatGPT, should not be listed as authors. For more information see the policy on Use of ChatGPT and generative AI tools.

    2.3 Acknowledgements

    All contributors who do not meet the criteria for authorship should be listed in an Acknowledgements section. Examples of those who might be acknowledged include a person who provided purely technical help, or a department chair who provided only general support.

    Please supply any personal acknowledgements separately to the main text to facilitate anonymous peer review.

    2.3.1 Third party submissions

    Where an individual who is not listed as an author submits a manuscript on behalf of the author(s), a statement must be included in the Acknowledgements section of the manuscript and in the accompanying cover letter. The statements must:

    • Disclose this type of editorial assistance – including the individual’s name, company and level of input
    • Identify any entities that paid for this assistance
    • Confirm that the listed authors have authorized the submission of their manuscript via third party and approved any statements or declarations, e.g. conflicting interests, funding, etc.

    Where appropriate, SAGE reserves the right to deny consideration to manuscripts submitted by a third party rather than by the authors themselves.

    2.3.2 Writing assistance

    Individuals who provided writing assistance, e.g. from a specialist communications company, do not qualify as authors and so should be included in the Acknowledgements section. Authors must disclose any writing assistance – including the individual’s name, company and level of input – and identify the entity that paid for this assistance. It is not necessary to disclose use of language polishing services.

    2.4 Funding

    Statistical Methods in Medical Research requires all authors to acknowledge their funding in a consistent fashion under a separate heading. Please visit the Funding Acknowledgements page on the SAGE Journal Author Gateway to confirm the format of the acknowledgment text in the event of funding, or state that: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. 

    2.5 Declaration of conflicting interests

    It is the policy of Statistical Methods in Medical Research to require a declaration of conflicting interests from all authors enabling a statement to be carried within the paginated pages of all published articles.

    Please ensure that a ‘Declaration of Conflicting Interests’ statement is included at the end of your manuscript, after any acknowledgements and prior to the references. If no conflict exists, please state that ‘The Author(s) declare(s) that there is no conflict of interest’. For guidance on conflict of interest statements, please see the ICMJE recommendations here.

    2.6 Research ethics and patient consent

    Medical research involving human subjects must be conducted according to the World Medical Association Declaration of Helsinki.

    Submitted manuscripts should conform to the ICMJE Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals, and all papers reporting animal and/or human studies must state in the methods section that the relevant Ethics Committee or Institutional Review Board provided (or waived) approval. Please ensure that you have provided the full name and institution of the review committee, in addition to the approval number.

    For research articles, authors are also required to state in the methods section whether participants provided informed consent and whether the consent was written or verbal.

    Information on informed consent to report individual cases or case series should be included in the manuscript text. A statement is required regarding whether written informed consent for patient information and images to be published was provided by the patient(s) or a legally authorized representative. Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The Journal requests that you confirm to us, in writing, that you have obtained written informed consent but the written consent itself should be held by the authors/investigators themselves, for example in a patient’s hospital record. The confirmatory letter may be uploaded with your submission as a separate file.

    Please also refer to the ICMJE Recommendations for the Protection of Research Participants.

    2.7 Clinical trials

    Statistical Methods in Medical Research conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first patient enrolment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.

    2.8 Reporting guidelines

    The relevant EQUATOR Network reporting guidelines should be followed depending on the type of study. For example, all randomized controlled trials submitted for publication should include a completed CONSORT flow chart as a cited figure and the completed CONSORT checklist should be uploaded with your submission as a supplementary file. Systematic reviews and meta-analyses should include the completed PRISMA flow chart as a cited figure and the completed PRISMA checklist should be uploaded with your submission as a supplementary file. The EQUATOR wizard can help you identify the appropriate guideline.

    Other resources can be found at NLM’s Research Reporting Guidelines and Initiatives.

    2.9 Data

    The journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the SAGE Research Data policy pages.

    Subject to appropriate ethical and legal considerations, authors are encouraged to:

    • share your research data in a relevant public data repository
    • include a data availability statement linking to your data. If it is not possible to share your data, we encourage you to consider using the statement to explain why it cannot be shared.
    • cite this data in your research

    Statistical Methods in Medical Research requests all authors submitting any primary data used in their research articles [“alongside their article submissions” or “if the articles are accepted”] to be published in the online version of the journal, or provide detailed information in their articles on how the data can be obtained. This information should include links to third-party data repositories or detailed contact information for third-party data sources. Data available only on an author-maintained website will need to be loaded onto either the journal’s platform or a third-party platform to ensure continuing accessibility. Examples of data types include but are not limited to statistical data files, replication code, text files, audio files, images, videos, appendices, and additional charts and graphs necessary to understand the original research. The editor can also grant exceptions for data that cannot legally or ethically be released. All data submitted should comply with Institutional or Ethical Review Board requirements and applicable government regulations.

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    3. Publishing Policies

    3.1 Publication ethics

    SAGE is committed to upholding the integrity of the academic record. We encourage authors to refer to the Committee on Publication Ethics’ International Standards for Authors and view the Publication Ethics page on the SAGE Author Gateway.

    3.1.1 Plagiarism

    Statistical Methods in Medical Research and SAGE take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. We seek to protect the rights of our authors and we always investigate claims of plagiarism or misuse of published articles. Equally, we seek to protect the reputation of the journal against malpractice. Submitted articles may be checked with duplication-checking software. Where an article, for example, is found to have plagiarised other work or included third-party copyright material without permission or with insufficient acknowledgement, or where the authorship of the article is contested, we reserve the right to take action including, but not limited to: publishing an erratum or corrigendum (correction); retracting the article; taking up the matter with the head of department or dean of the author's institution and/or relevant academic bodies or societies; or taking appropriate legal action.

    3.1.2 Prior publication

    If material has been previously published it is not generally acceptable for publication in a SAGE journal. However, there are certain circumstances where previously published material can be considered for publication. Please refer to the guidance on the SAGE Author Gateway or if in doubt, contact the Editor at the address given below.

    3.2 Contributor's publishing agreement

    Before publication, SAGE requires the author as the rights holder to sign a Journal Contributor’s Publishing Agreement. SAGE’s Journal Contributor’s Publishing Agreement is an exclusive licence agreement which means that the author retains copyright in the work but grants SAGE the sole and exclusive right and licence to publish for the full legal term of copyright. Exceptions may exist where an assignment of copyright is required or preferred by a proprietor other than SAGE. In this case copyright in the work will be assigned from the author to the society. For more information please visit the SAGE Author Gateway

    3.3 Open access and author archiving

    Statistical Methods in Medical Research offers optional open access publishing via the Sage Choice programme and Open Access agreements, where authors can publish open access either discounted or free of charge depending on the agreement with Sage. Find out if your institution is participating by visiting Open Access Agreements at Sage. For more information on Open Access publishing options at Sage please visit Sage Open Access. For information on funding body compliance, and depositing your article in repositories, please visit Sage’s Author Archiving and Re-Use Guidelines and Publishing Policies.

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    4. Preparing your manuscript for submission

    4.1 Formatting

    The preferred format for your manuscript is Word. LaTeX files are also accepted. The text should be double-spaced throughout and with a minimum of 3cm for left and right hand margins and 5cm at head and foot. Text should be standard 10 or 12 point.Word and (La)Tex templates are available on the Manuscript Submission Guidelines page of our Author Gateway.We recommend using Bibitem rather than Bibtex for reference formatting.

    4.2 Artwork, figures and other graphics

    For guidance on the preparation of illustrations, pictures and graphs in electronic format, please visit SAGE’s Manuscript Submission Guidelines.  

    Images should be supplied as bitmap based files (i.e. with .tiff or .jpeg extension) with a resolution of at least 300 dpi (dots per inch). Line art should be supplied as vector-based, separate .eps files (not as .tiff files, and not only inserted in the Word or pdf file), with a resolution of 600 dpi. Images should be clear, in focus, free of pixilation and not too light or dark.

    In text: tables and figures are either inserted as part of a sentence, for example table 1 or in parentheses for example (figure 1). Each table should carry a descriptive heading. Each figure should be submitted electronically.

    Line drawings should be black and white. Figures should ideally be produced for a reduction of one third i.e. 3:2 or 150:100 mm.

    Figures supplied in colour will appear in colour online regardless of whether or not these illustrations are reproduced in colour in the printed version. For specifically requested colour reproduction in print, you will receive information regarding the costs from SAGE after receipt of your accepted article.

    4.3 Supplemental material

    This journal is able to host additional materials online (e.g. datasets, podcasts, videos, images etc) alongside the full-text of the article. For more information please refer to our guidelines on submitting supplemental files

    4.4 Reference style

    Statistical Methods in Medical Research adheres to the SAGE Vancouver reference style. View the SAGE Vancouver guidelines to ensure your manuscript conforms to this reference style. Manuscripts with references not in this style will be returned.

    If you use EndNote to manage references, you can download the SAGE Vancouver EndNote output file.

    4.5 Journal Layout

    When preparing your paper:
    - Use the minimum formatting.
    - Roman, bold and italic type can be used, but use only one typeface and size.
    - Capitals should be used only where they are to appear in the finished text.
    - The text should be ranged left and unjustified, with hyphenation cancelled.
    - Indents, underlining and tabs should be avoided unless absolutely necessary.
    - Headings and paragraphs should be separated by two carriage returns.
    - There should be only one space between words and only one space after any punctuation.

    Abbreviations should be spelled out when first used in the text. Full stops should be used in lower case abbreviations (e.g., i.e.) but not for capitals (SAS, ANOVA). Spelling should follow the Oxford Dictionary.

    Mathematical: All vectors and matrices should be shown in bold type. Numbers below 10 should be written out in the text unless used in conjunction with units (e.g. three apples, 4 kg).

    Full points (not commas) should be used for decimals. For numbers less than one, a nought should be inserted before the decimal point. Use spaces (not commas) within numbers (e.g. 10 000, 0.125 275).

    4.6 English language editing services

    Authors seeking assistance with English language editing, translation, or figure and manuscript formatting to fit the journal’s specifications should consider using SAGE Language Services. Visit SAGE Language Services on our Journal Author Gateway for further information.

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    5. Submitting your manuscript

    Statistical Methods in Medical Research is hosted on SAGE Track, a web based online submission and peer review system powered by ScholarOne™ Manuscripts. Visit https://mc.manuscriptcentral.com/smmr to login and submit your article online.

    IMPORTANT: Please check whether you already have an account in the system before trying to create a new one. If you have reviewed or authored for the journal in the past year it is likely that you will have had an account created.  For further guidance on submitting your manuscript online please visit ScholarOne Online Help.

    5.1 ORCID

    As part of our commitment to ensuring an ethical, transparent and fair peer review process SAGE has become a supporting member of ORCID, the Open Researcher and Contributor ID. ORCID provides a persistent digital identifier that distinguishes researchers from every other researcher and, through integration in key research workflows such as manuscript and grant submission, supports automated linkages between researchers and their professional activities ensuring that their work is recognized.

    The collection of ORCID iDs from corresponding authors is now part of the submission process of this journal. If you already have an ORCID iD you will be asked to associate that to your submission during the online submission process. We also strongly encourage all co-authors to link their ORCID ID to their accounts in our online peer review platforms. It takes seconds to do: click the link when prompted, sign into your ORCID account and our systems are automatically updated. Your ORCID iD will become part of your accepted publication’s metadata, making your work attributable to you and only you. Your ORCID iD is published with your article so that fellow researchers reading your work can link to your ORCID profile and from there link to your other publications.

    If you do not already have an ORCID iD please follow this link to create one or visit our ORCID homepage to learn more.
     

    5.2 Information required for completing your submission

    You will be asked to provide contact details and academic affiliations for all co-authors via the submission system and identify who is to be the corresponding author. These details must match what appears on your manuscript. The affiliation listed in the manuscript should be the institution where the research was conducted. If an author has moved to a new institution since completing the research, the new affiliation can be included in a manuscript note at the end of the paper. At this stage please ensure you have included all the required statements and declarations and uploaded any additional supplementary files (including reporting guidelines where relevant).

    5.3 Permissions

    Please also ensure that you have obtained any necessary permission from copyright holders for reproducing any illustrations, tables, figures or lengthy quotations previously published elsewhere. For further information including guidance on fair dealing for criticism and review, please see the Copyright and Permissions page on the SAGE Author Gateway.

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    6. On acceptance and publication

    6.1 SAGE Production

    Your SAGE Production Editor will keep you informed as to your article’s progress throughout the production process. Proofs will be made available to the corresponding author via our editing portal SAGE Edit or by email, and corrections should be made directly or notified to us promptly. Authors are reminded to check their proofs carefully to confirm that all author information, including names, affiliations, sequence and contact details are correct, and that Funding and Conflict of Interest statements, if any, are accurate.

    6.2 Online First publication

    Online First allows final articles (completed and approved articles awaiting assignment to a future issue) to be published online prior to their inclusion in a journal issue, which significantly reduces the lead time between submission and publication. Visit the SAGE Journals help page for more details, including how to cite Online First articles.

    6.3 Access to your published article

    SAGE provides authors with online access to their final article.

    6.4 Promoting your article

    Publication is not the end of the process! You can help disseminate your paper and ensure it is as widely read and cited as possible. The SAGE Author Gateway has numerous resources to help you promote your work. Visit the Promote Your Article page on the Gateway for tips and advice. 

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    7. Further information

    Any correspondence, queries or additional requests for information on the manuscript submission process should be sent to the Statistical Methods in Medical Research editorial office at editors.smmr@gmail.com.

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