Therapeutic Advances in Cardiovascular Disease
Launched in 2007, Therapeutic Advances in Cardiovascular Disease is a gold open access journal publishing clinically focused cardiovascular research that optimises treatment strategies across the care pathway, enables real-world implementation, and improves patient and service outcomes. All articles are made freely available online upon publication, supporting the rapid and global dissemination of evidence that informs patient care.
The journal publishes original research articles, systematic and narrative reviews, consensus statements and guidelines, study protocols, and case reports/series that address how cardiovascular disease is treated in practice, with particular emphasis on studies that clarify clinical decision-making, optimise therapeutic strategies, and improve outcomes across diverse patient populations. For more information about article types and topical priorities, please refer to the Aims and Scope page.
Our goal is to publish novel research, even if it represents an incremental advance. While our primary focus is on ensuring sound scientific practices, including adherence to ethical standards and the use of robust, transparent, and reproducible methodologies, we recognise the value of incremental contributions to the field. We care more about the quality and reliability of the contribution an article makes than we do the size of that contribution. Therapeutic Advances in Cardiovascular Disease evaluates manuscripts based on how the research was conducted and reported.
All submissions undergo rigorous peer review and are evaluated for clinical relevance, methodological quality, and therapeutic impact. Therapeutic Advances in Cardiovascular Disease is indexed in MEDLINE, PubMed Central, Clarivate Analytics' Emerging Sources Citation Index (ESCI), and Scopus, and is a member of the Committee on Publication Ethics (COPE).
Accessible formats and article enhancements
Therapeutic Advances in Cardiovascular Disease also offers alternative article formats including Plain Language Summaries of Publications (PLS-Ps; standalone, peer-reviewed summaries of previously published articles), and podcast and clinical image articles, as well as article enhancements such as video abstracts and infographics. These formats extend the journal's educational reach, helping clinicians, generalist healthcare professionals, patients, caregivers, and policymakers engage with evidence, and align with our commitment to inclusive, real-world communication. For queries about these formats, please contact Dr. Amy Goundry at amy.goundry@sagepub.co.uk prior to submission.
Diversity, Equity and Inclusion statement
Therapeutic Advances in Cardiovascular Disease promotes inclusive, open science that reflects the disciplinary, human, and geographic diversity of the research community.
Diversity as a core value embodies inclusiveness, mutual respect, and multiple perspectives.
We welcome editors, editorial board members, peer reviewers, and authors from all backgrounds, cultures, ethnicities, nationalities, races, religions, sexes, sexual orientations, gender identities, mental or physical (dis)abilities, ages, career stages, socioeconomic status, or any other individual status.
We are committed to continually improving our editorial and review processes whilst playing our part in eradicating bias and inequality in all forms.
Submission information
Submit your manuscript at http://mc.manuscriptcentral.com/tac.
Please see the Submission Guidelines for more information on preparing and submitting your article.
Open access information
The article processing charge (APC) for this journal is currently $3000 USD*.
*APC for original research articles, brief reports, systematic reviews and meta-analyses, narrative reviews, study protocols, and case reports/series.
Pre-submission queries
Pre-submission enquiries are welcome. Authors proposing accessible formats (i.e., PLS-Ps and podcast or clinical image articles) should contact the Managing Editor before submitting. We also invite general questions about scope alignment, clinical positioning, and submissions to current Special Collections.
Please direct pre-submission queries to Dr. Amy Goundry at amy.goundry@sagepub.co.uk.
Subject line: TAK Pre-Submission Query — [Article Type] — [Special Collection, if any]
For questions about a submitted paper or to request an extension for a review or revision, please contact the journal's editorial office at cardio@sagepub.co.uk.
Therapeutic Advances in Cardiovascular Disease is a peer-reviewed, gold open access journal dedicated to publishing clinically focused cardiovascular research that optimises treatment strategies across the care pathway, enables real-world implementation, and improves patient and service outcomes.
The journal covers the full spectrum of cardiovascular care, from prevention and diagnosis to treatment optimisation and long-term management, helping clinicians choose, tailor, and refine therapies in real-world practice and across diverse patient populations. This includes decision-relevant health systems and services research on models of care, implementation strategies, service delivery, equity of access, and the translation of evidence into practice. Such research should demonstrably inform treatment choices or care pathways and report patient- or service-level outcomes.
The journal considers:
- Original research (observational, interventional, comparative-effectiveness, implementation, and service-delivery studies) that evaluate therapies, care pathways, or models of care and report clinical, utilisation, equity, or implementation outcomes.
- Systematic and narrative reviews that clarify treatment choices or care pathways.
- Consensus statements/guidelines that translate evidence into actionable treatment algorithms.
- Study protocols for comparative-effectiveness or implementation studies with direct therapeutic relevance.
- Case reports and series with clear management implications (e.g., change in treatment selection, timing, dose, sequencing, or monitoring), and follow-up outcomes where feasible.
Topics of particular interest include:
- Comparative effectiveness and treatment strategies
- Therapeutic optimisation (dose, duration, combinations, sequencing)
- Precision/personalised approaches with clinical validation
- Long-term outcomes and equity in therapy delivery
- Implementation science and service-model evaluations (e.g., care pathways, digital decision support, pharmacist-led titration) linked to clinical or utilisation outcomes
- Emerging technologies (e.g., imaging, AI, devices) with demonstrable impact on clinical decisions (selection, timing, monitoring) and, where possible, patient outcomes
Therapeutic Advances in Cardiovascular Disease actively encourages well-designed studies reporting null or neutral results when they clearly inform practice.
Preclinical or purely mechanistic/biomarker-discovery work without clinical validation is not considered (e.g., animal or in vitro studies; omics/microRNA discovery without patient-level decision impact). Economic or policy analyses without accompanying clinical, utilisation, or implementation outcomes; descriptive audits without decision relevance; and purely epidemiological reports are out of scope.
Reporting and transparency standards
Where applicable, submissions should adhere to established reporting guidelines and best practice:
- CONSORT for randomised trials, STROBE for observational studies, PRISMA for systematic reviews, SPIRIT for protocols, and CARE for care reports/series.
- Trial registration in a WHO-approved registry for interventional studies at or before first patient enrolment.
- Clear statements on ethical considerations and consent to participate.
- Data availability and declaration of conflicting interest statements consistent with ICMJE recommendations.
Audience and reach
Therapeutic Advances in Cardiovascular Disease serves an international readership of clinicians, clinical researchers, healthcare professionals, and cardiovascular teams, offering rapid, global dissemination via gold open access.
Accessible formats and article enhancements
To maximise accessibility and impact, Therapeutic Advances in Cardiovascular Disease also supports a range of alternative article formats including Plain Language Summaries of Publications (PLS-Ps; standalone, peer-reviewed summaries of previously published articles) and podcast and clinical image articles. These formats extend the journal's educational reach, helping clinicians, generalist healthcare professionals, patients, caregivers, and policymakers engage with evidence, and align with our commitment to inclusive, real-world communication. For queries about these formats, please contact Dr. Amy Goundry at amy.goundry@sagepub.co.uk prior to submission.
| Amy Goundry, PhD | SAGE Publications Ltd, UK |
| Atharva Gajanan Gajalkar | SAGE Publishing, India |
| Arduino Mangoni MD, PhD | Flinders Medical Centre and Flinders University, Bedford Park, Australia |
| Phyo Myint MBBS, MD, FRCP (Edin) | Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, United Kingdom |
| Robert J. Chen, MD, MPH | Stanford University School of Medicine, Cardiothoracic Surgery, USA |
| Dario Gregori, PhD, FTOS, FACN | University of Padua, Italy |
| Chenghui Li, PhD | University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA |
| F. Aaysha Cader MBBS, MD, MRCP (UK) | Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh |
| Luis Alcocer MD | Hospital General of Mexico, Mexico City (Magdalena Contreras), Mexico |
| Dr. Ahmed Alsinbili | Milton Keynes University Hospital Oxford, UK |
| Matteo Beltrami | Careggi University Hospital, Florence, Italy |
| Josephine P. Briggs MD | National Center for Complementary and Integrative Health (NCCIH), Maryland, USA |
| Victoria M. Cachofeiro MD | Universidad Complutense, Madrid, Spain |
| Jose Cangiano MD | Sociedad de Nefrología e Hipertensión de Puerto Rico, Puerto Rico |
| Larisa Cavallari | University of Florida, Gainesville, FL, USA |
| Angel Chamorro MD | University of Barcelona, Spain |
| Thomas M. Coffman MD | Duke University Medical Center, Durham, North Carolina, USA |
| Zainab A. Dakhil, FIMBS Cardiol, FIBMS Med, FABHS Med, DM Chest diseases, DM Med, MBChB, MACC, MESC, | Ibn Al Bitar Cardiac Centre, Al-Kindy College of Medicine, Iraq |
| Kevin P Davy Ph.D. | Virginia Polytechnic Institute and State University, Blacksburg, USA |
| Javier Diez MD | University of Navarra, Pamplona, Spain |
| Bonita Falkner MD | Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA |
| Gregory Fink MD | Michigan State University, East Lansing, Michigan, USA |
| John M Flack MD | Southern Illinois University, Illinois, USA |
| John Floras MD | University of Toronto, Toronto, Ontario, Canada |
| Toshiro Fujita MD | The University of Tokyo, Tokyo, Japan |
| Cristina Gavina MD, PhD | Hospital Pedro Hispano, Portugal |
| Randolph L Geary MD | Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA |
| Vadim Genkel | South-Ural State Medical University, Chelyabinsk, Russia |
| Seyed Mehrdad Hamrahian, MD | Thomas Jefferson University in Philadelphia, PA, USA |
| Parta Hatamizadeh | University of Florida Health, Florida, USA |
| Pedro Jose MD | Georgetown University Medical Center, Washington D.C., USA |
| Luis Juncos MD | National University of Cordoba, Cordoba, Argentina |
| Efstratios Koutroumpakis, MD | MD Anderson Cancer Centre, University of Texas, USA |
| Jose E. Krieger MD | University of Sco Paulo Medical School, Sco Paulo, Brazil |
| Pavel J Levy MD | Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA |
| Anastasios (Tassos) Lymperopoulos | NSU College of Pharmacy, Nova Southeastern University, United States |
| Giuseppe Mancia MD, PhD | University of Milan - Bicocca, Monza, Italy |
| Jawahar L Mehta MD, PhD | University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA |
| Nicola Mumoli, MD | Ospedale Civile di Busto Arsizio, ASST Valle Olona, Busto Arsizio, Italy |
| Mohan Raizada MD, PhD | University of Florida, Florida, USA |
| Josep Redon MD, PhD | Hospital Clinico Universitario, Universidad de Valencia, Valencia, Spain |
| Kathryn Sandberg PhD | Georgetown University, Washington D.C., USA |
| Rameen Shakur MD, PhD(Cantab), FRSA, FIBMS, FRSPH | University of Brighton, Brighton, United Kingdom |
| Rhian M. Touyz MBBCh, MSc, PhD | University of Glasgow, Glasgow, Scotland, UK |
| Jasmina Varagic MD, PhD | National Heart, Lung, and Blood Institute (NHLBI), Bethesda, USA |
| George Vauquelin MD, PHD | Vrije Universiteit Brussels, Brussels, Belgium |
| Massimo Volpe MD | Ospedale Sant'Andrea, Univerisity "La Sapienza" Rome, Italy |
| R Clinton Webb PhD, MS | Medical College of Georgia, Augusta, Georgia, USA |
| Matthew R. Weir MD | University of Maryland School of Medicine, Baltimore, Maryland, USA |
| Bryan Williams MD | University of Leicester, Leicester, UK |
| Yoram Yagil PhD, MD | Ben-Gurion University, Ashkelon, Israel |
| Irving Zucker PhD, MD | University of Nebraska Medical Center, Omaha, Nebraska, USA |
| Avinash Anantharaj, MBBS, MD, DM, PDF | Jawaharlal Institute of Post graduate Medical Education and Research (JIPMER) Puducherry, India |
| Zhipeng Bao, MSc | The First Affiliated Hospital of Nanjing Medical University, Nanjing, China |
| Moustafa Dawood, MBBCh, MSc, PhD, FSCAI | Alexandria University, Alexandria, Egypt |
| Doaa El Amrousy, MD | Tanta University, Egypt |
| Tuncay Güzel, MD | Health Science University, Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey |
| Raymond Haddad, MD, MHSc, PhDc, FPICS | Marie Lannelongue Hospital, Université Paris-Saclay, Le Plessis-Robinson, France |
| Jibran Ikram, MD | Heart Vascular & Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA |
| Rabia Islam, MBBS | Harvard TH-chan school of public health, Boston, USA |
| Yasuhiko Kawaguchi, MD | London Health Sciences Centre, Western University, London, ON, Canada |
| Kiyonori Kobayashi, PT, MSc | Nagoya University Hospital, Nagoya, Japan |
| Krishna Prasad Kurpad, MBBS | University of Texas Medical Branch, Galveston, TX, USA |
| Wael Saade, MD | La Sapienza University of Rome, Rome, Italy |
| Sandeep Ajoy Saha, MD, MS, FACC, FHRS | Oregon Heart Center, Salem, Oregon, USA |
| Alon Shechter, MD, MHA | Rabin Medical Center, Israel |
| Zhanhao Su, MD, PhD | Provincial People's Hospital, Guangzhou, China |
| Irfan Ullah, MBBS, MPH | University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA |